Equity analysts weigh these growth metrics heavily in revising valuation models upward. If you're looking to bet against a company, the process is more complex. You'll need access to an options trading platform, or a broker who will allow you to “go short” a share of stock by lending you the shares to sell. The process of shorting a stock can be found at this resource. Otherwise, if your broker allows you to trade options, you can either buy a put option, or sell a call option at a strike price above where shares are currently trading – either way it allows you to profit off of the share price decline. U.S.-based Tempus AI (TEM) experienced a notable 9% surge in its stock price on Wednesday. This uptick occurred without any company-specific news. However, President Trumpâs recent executive order promoting the use of AI to tackle pediatric, adolescent, and young adult cancers may have driven the stock higher. Trading desks observe that Tempus stock price correlated 0.72 with the broader NASDAQ Biotech Index in June, revealing sector-based sentiment influence. Macro catalysts like FDA approvals and AI-driven research funding could shift valuation in the coming weeks.